Annals of Surgery

Genome-wide Discovery of a Novel Gene-expression Signature for the Identification of Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma.

Authors Fuminori Sonohara; Feng Gao; Naoki Iwata; Mitsuro Kanda; Masahiko Koike; Naoki Takahashi; Yasuhide Yamada; Yasuhiro Kodera; Wang X*; Ajay Goel Annals of Surgery 2017, doi:10.1097/SLA.0000000000002622 Objective This study aimed to develop a gene-expression signature for identification of lymph node (LN) metastasis in esophageal squamous cell carcinoma (ESCC) patients. Summary of Background Data LN metastasis is recognized as the most important independent risk factor for therapeutic decision-making of ESCC patients.

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